Jessica Shiu, MD, PhD

Speaker Details
  • Abstract Title

    Multimodal Analyses of Stable Vitiligo Skin Identify Tissue Interactions That Control Disease Persistence

  • Abstract Take Home Message

    Stress keratinocytes exhibit a unique signature – metabolic preferences for oxidative phosphorylation, expression of stress keratins, alarmins and CXCL9/10 and diminished WNT signaling – and likely drive the persistence of white patches in vitiligo. They may be targeted for therapy in the future.

  • Additional Authors

    Lihua Zhang, Griffin Lentsch ,  Jessica L Flesher, Suoqin Jin, Christopher Polleys, Seong Jin Jo, Craig Mizzoni, Pezhman Mobasher,  Jasmine Kwan, Francisca Ruis-Diaz, Bruce J Tromberg, Irene Georgakoudi, Qing Nie, Mihaela Balu, Anand K Ganesan

  • Disclosures

    No relevant disclosures.