Marcella Willemsen, MSc

Vitiligo Up-and-Coming Invited Speaker

Speaker Details
  • Presentation Title

    Impaired IFN-γ-induced PD-L1 Expression on Human Vitiligo Melanocytes

  • Summary

    The lack of PD-L1 upregulation by melanocytes in the presence of IFN-γ-producing T cells shows that melanocytes do not confer protection against T cell attack during vitiligo pathogenesis. Manipulating PD-1/PD-L1 signaling, therefore, may be a therapeutic option for human vitiligo.

  • Additional Authors

    Gabrielle Krebbers, Esther P.M. Tjin, Karin J. Willemsen, Alesha Louis, Veronique A.L. Konijn, Vidhya S. Narayan, Nicoline F. Post, Walbert J. Bakker, Cornelis J.M. Melief, Marcel W. Bekkenk, Rosalie M. Luiten

  • Disclosures

    Nothing to disclose.